Myeloproliferative disorder causing overproduction of red blood cells, increasing blood thickness and clotting risk. JAK2 mutation in most cases. Symptoms include headaches, dizziness, pruritus (especially after bathing), ruddy complexion, splenomegaly, and increased risk of thrombosis. Can transform to myelofibrosis or acute leukemia.
Requiring peripheral blood or bone marrow stem cell transplant or chemotherapy for symptom control (100% continues for 6 months post-treatment, then re-evaluate)
Requiring phlebotomy 6 or more times per 12-month period or molecularly targeted therapy for controlling RBC count
Requiring phlebotomy 4-5 times per 12-month period, or continuous biologic therapy/myelosuppressive agents to maintain platelets <200,000 or WBC <12,000
Requiring phlebotomy 3 or fewer times per 12-month period or requiring biologic therapy or interferon intermittently to maintain normal blood values
Medical Evidence
Current diagnosis from a qualified healthcare provider, medical records documenting symptoms and treatment history
Service Connection
Evidence linking your condition to military service (service treatment records, incident reports, or nexus letter)
Personal Statement
Your detailed account of how polycythemia vera affects your daily life and when symptoms began
Lay Evidence
Buddy letters from fellow service members or family who can corroborate your symptoms
During your Compensation & Pension exam for polycythemia vera, examiners will assess your symptoms against the rating criteria above.
Be specific: Describe your worst day, not your average day
Document everything: Bring copies of all medical records and evidence
Functional impact: Explain how symptoms affect work, sleep, and daily activities
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