Severe neutropenia (very low neutrophil count) causing extreme infection vulnerability. Often drug-induced or autoimmune. Absolute neutrophil count (ANC) <500/µL defines severe risk. Symptoms include fever, mouth ulcers, sore throat, and recurrent infections. Life-threatening condition requiring immediate treatment and often hospitalization.
Requiring bone marrow transplant (100% continues for 6 months post-discharge, then re-evaluate); or infections recurring on average at least once every 6 weeks per year
Requiring intermittent myeloid growth factors (G-CSF or GM-CSF) or continuous immunosuppressive therapy to maintain ANC >500 but <1000/µL; or infections recurring on average at least once every 3 months
Requiring intermittent myeloid growth factors to maintain ANC >1000/µL; or infections recurring on average at least once per 12-month period but less than once every 3 months
Requiring continuous medication (antibiotics) for control; or intermittent myeloid growth factor to maintain ANC ≥1500/µL
Medical Evidence
Current diagnosis from a qualified healthcare provider, medical records documenting symptoms and treatment history
Service Connection
Evidence linking your condition to military service (service treatment records, incident reports, or nexus letter)
Personal Statement
Your detailed account of how agranulocytosis, acquired affects your daily life and when symptoms began
Lay Evidence
Buddy letters from fellow service members or family who can corroborate your symptoms
During your Compensation & Pension exam for agranulocytosis, acquired, examiners will assess your symptoms against the rating criteria above.
Be specific: Describe your worst day, not your average day
Document everything: Bring copies of all medical records and evidence
Functional impact: Explain how symptoms affect work, sleep, and daily activities
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